DESCRIPTION

Wellbutrin XL (Bupropion Hydrochloride 24H ER Tablet) is an Rx medication that is used to treat major depressive disorder and seasonal affective disorder. This medication may also be used to treat attention deficit hyperactivity disorder (ADHD), or to help people quit smoking by decreasing cravings and nicotine withdrawal effects. It may also be used along with other mood stabilizers to treat bipolar disorder (depressive phase). It may also be used to treat anxiety in people with depression.

Bupropion may also be used for purposes not listed in this leaflet, but must only be used only if it has been so prescribed by your health care professional. Bupropion is the generic form of Wellbutrin (we are happy to be able to offer you both forms) which works by affecting two chemicals in the brain that are believed to help regulate your mood (dopamine and norepinephrine). Wellbutrin is generally well tolerated.

Take this medication by mouth with or without food as directed by your doctor, usually once daily in the morning. If you have stomach upset, you may take this medication with or after a meal or snack. Taking this medication late in the day may cause trouble sleeping (insomnia). Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Do not crush or chew extended-release tablets. Doing so can release all of the drug at once, thereby increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

PACKAGING

Wellbutrin XL (Bupropion Hydrochloride 24H ER Tablet) comes from Canada and is manufactured by Valeant. This medication is available in Brand form – Wellbutrin XL - in doses of 150mg and 300mg in quantities of 90 and 180 tablets and generic form - Bupropion Hydrochloride 24H ER Tablet was manufactured by Mylan in Canada - also in doses of 150mg and 300mg in the quantities of 90 tablets.

Please note that the manufacturing country and the manufacturer may vary depending on the availability.

DELIVERY

The standard shipping fee is a flat rate of $10.00. Orders are normally dispatched in 2-3 working days after the order is processed. Your package will be delivered by regular mail in 10-14 business days after it is shipped out.

For more information and further assistance, please feel free to Customer Service at 604-581-4000 or email us at customerservice@canadawidepharmacy.com.

SIDE-EFFECTS

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high.

Tell your doctor right away if you have any serious side effects, including: fast/pounding/irregular heartbeat, mental/mood changes (such as anxiety, agitation, confusion, unusual behavior/thinking, memory loss), unusual weight loss or gain. Stop taking bupropion and get medical help right away if you have any very serious side effects, including: seizure, eye pain/swelling/redness, widened pupils, vision changes (such as seeing rainbows around lights at night, blurred vision).

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), painful sores in the mouth/around the eyes, severe dizziness, trouble breathing. Other possible side-effects include: Dry mouth, sore throat, dizziness, nausea, vomiting, ringing in the ears, headache, decreased appetite, weight loss, constipation, trouble sleeping, increased sweating, or shaking (tremor) may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. An empty tablet shell may appear in your stool. This effect is harmless because your body has already absorbed the medication. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

SAFETY

Do not take Wellbutrin XL (Bupropion Hydrochloride 24H ER Tablet) if you are allergic to it or if you have any other allergies. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/non-prescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: pimozide and tamoxifen. Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Ask your doctor when to start or stop taking this medication.

This medication may interfere with certain medical/laboratory tests (including brain scan for Parkinson's disease, urine screening for amphetamines), possibly causing false results. Tell laboratory personnel and all your doctors you use this drug.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, heart disease, high blood pressure, kidney problems, liver disease, use/abuse of drugs/alcohol, seizures or conditions that increase your risk of seizures (including brain/head injury, brain tumor, eating disorders such as bulimia/anorexia nervosa), personal or family history of glaucoma (angle-closure type).

This medication should not be used if you are suddenly stopping regular use of sedatives (including benzodiazepines such as lorazepam), drugs used to treat seizures, or alcohol. Doing so may increase your risk of seizures.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages. Alcohol can increase your risk of dizziness or seizures.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, non-prescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially dizziness and memory loss. Dizziness can increase the risk of falling.

During pregnancy, this medication should be used only when clearly needed. Since untreated mental/mood problems (such as depression, seasonal affective disorder, bipolar disorder) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.